This international consensus document presents the outcomes of an expert panel discussion, convened in October 2023. The discussion aimed to provide best-practice recommendations on the assessment and management of venous and arteriovenous leg ulcers. To this end, the panellists explored the accurate assessment of the venous and arterial aetiologies underlying leg ulceration, as well as the optimal safe and effective management of venous or arteriovenous ulceration using compression therapy as part of a holistic care plan. This consensus document is intended to complement existing published guidance on the management of venous ulceration and use of compression therapy,1,2,3,4 primarily by filling gaps in earlier guidelines on the assessment and management of leg ulcers with a mixed aetiology caused by combined arterial and venous insufficiency (CAVI). This consensus document has been written for a multidisciplinary readership of generalist and specialist health professionals, including physicians, podiatrists, nurses and allied health professionals, such as physical and occupational therapists. It aims to be inclusive and international, with a relevance to all healthcare settings and consideration for variations in practice; access to resources; and the way services are designed, provided and reimbursed in the medical systems throughout the world. It is hoped that the recommendations in this consensus document will provide health professionals with the skills and confidence to accurately assess chronic venous and/or arterial insufficiency and deliver compression therapy in a timely, safe and effective manner.