In this chapter the main aspects of the heat transfer phenomena of nucleate pool boiling with smooth and enhanced surfaces are presented and discussed. This chapter first covers pool boiling on smooth surfaces and afterwards pool boiling on enhanced surfaces. Also, a section on boiling of refrigerant mixtures presents a method to calculate the effects of mass transfer of refrigerant mixtures on the pool boiling heat transfer. For both smooth and enhanced surfaces, first are described the physical processes guiding the heat transfer phenomena. These points are then illustrated by a set of experimental data which allows one to observe the effect of each experimental parameter on the heat transfer process. A set of selected nucleate pool boiling heat transfer correlations is then presented, discussed and compared. Through this presentation, the most important aspects of nucleate pool boiling will be highlighted and explained, and thus provide a guide to the selection of the most appropriate prediction model for the application.