Background : Widespread variation exists in pediatric critical care nutrition practices, largely because of the scarcity of evidence to guide best practice recommendations. Objective : The objective of this paper was to develop a list of topics to be prioritized for nutrition research in pediatric critical care in the next 10 years. Methods : A modified 3‐round Delphi process was undertaken by a newly established multidisciplinary group comprising 11 international researchers in the field of pediatric critical care nutrition. Items were ranked on a 5‐point Likert scale. Results : Forty‐five research topics (with a mean priority score >3(0‐5) were identified within the following 10 domains: the pathophysiology and impact of malnutrition in critical illness; nutrition assessment: nutrition risk assessment and biomarkers; accurate assessment of energy requirements in all phases of critical illness; the role of protein intake; the role of pharmaco‐nutrition; effective and safe delivery of enteral nutrition; enteral feeding intolerance: assessment and management; the role of parenteral nutrition; the impact of nutrition status and nutrition therapies on long‐term patient outcomes; and nutrition therapies for specific populations. Ten top research topics (that received a mean score >4(0‐5) were identified as the highest priority for research. Conclusions : This paper has identified important consensus‐derived priorities for clinical research in pediatric critical care nutrition. Future studies should determine topics that are a priority for patients and parents. Research funding should target these priority areas and promote an international collaborative approach to research in this field, with a focus on improving relevant patient outcomes.