Ethics by Design concerns the methods, algorithms and tools needed to endow autonomous agents with the capability to reason about the ethical aspects of their decisions, and the methods, tools and formalisms to guarantee that an agent’s behavior remains within given moral bounds. In this context some questions arise: How and to what extent can agents un-derstand the social reality in which they operate, and the other intelligences (AI, animals and humans) with which they co-exist? What are the ethical concerns in the emerging new forms of society, and how do we ensure the human dimen-sion is upheld in interactions and decisions by autonomous agents?. But overall, the central question is: “Can we, and should we, build ethically-aware agents?”