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Background: The present study aimed to examine the influence of psychosocial and demographic factors on health professionals’ intention to integrate complementary and integrative medicine (CIM) into hospital-based psychiatric clinical practice. It also sought to validate the theoretical model derived from our previous exploratory study. Method: A cross-sectional survey study using an online questionnaire sent to 4111 potential participants based on an adapted version of Triandis’ Theory of Interpersonal Behaviour (TIB). Results: Participants reported high levels of positive attitudes towards CIM, with 61.6 % of the 1561 respondents reporting previous use in clinical practice and 37.8 % having received formal CIM training. Analysis of professionals’ intention to use CIM revealed four influential psychosocial factors - affect, perceived social norms, descriptive norms and past behaviour (p < 0.0001) - and three significant demographic factors - older age, a managerial position and fewer years of clinical practice (p < 0.05). With an area under the ROC curve of 95.53 %, the resulting model showed high discriminatory power and excellent fit. Conclusions: These findings highlight the need for a supportive institutional environment to promote CIM. This requires the support of a wide range of professional leaders and the promotion of a shared CIM culture among healthcare professionals and interdisciplinary discussions.

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