Purpose: To describe health care professionals’ (HCPs’) perceptions of the implementation of an online mindfulness-based cancer recovery (eMBCR) program in the gyneco-oncology departments of two university hospitals in Switzerland. Methods: The study analyzed determinants drawn from the Consolidated Framework for Implementation Research (CFIR) using a deductive, semantic, thematic approach. Five focus groups were conducted with HCPs and managers (12 nurses, 6 physicians, and 1 psycho-oncologist). Results: Most HCPs supported integrating mindfulness meditation into cancer care, although some physicians viewed it as an alternative approach with insufficient evidence. Key facilitators included the presence of a center for integrative medicine within hospitals and the engagement of leaders and champions. Barriers related to time constraints, human resources, materials, and training were mentioned. Suggested strategies for successful implementation included hybrid program delivery (online and in person), context-specific adaptations (e.g., dosage), and securing stable funding for sustainability. Conclusion: This study highlights multilevel factors influencing the implementation of a mindfulness meditation intervention in the context of cancer care and offers strategies to enhance its long-term integration within hospital settings.