@article{Guha:15090, recid = {15090}, author = {Guha, Souvik and Sen, Subhabrata and Gremaud, Ludovic}, title = {Eco-friendly anaerobic oxidation of aryl diazo esters with heterocyclic N-oxide under ball milling : synthesis of 1,2-dicarbonyl systems}, publisher = {Royal Society of Chemistry (RSC)}, journal = {RSC Mechanochemistry}, address = {London, UK. 2024-10}, number = {ARTICLE}, pages = {9 p.}, abstract = {Herein we report anaerobic oxidation of metal carbenoids generated from aryl diazo esters under ball milling with heterocyclic N-oxide in the presence of catalytic copper(I) to afford 1,2-dicarbonyls in excellent yield. Efficiently progressing across a diverse spectrum of substrates, the reaction demonstrates exceptional tolerance to a variety of functional groups, under mild reaction conditions, at low catalyst loading and minimum volume of solvent as a Liquid-Assisted Grinding (LAG) auxiliary thereby demonstrating a practical strategy to generate these molecules.}, url = {http://arodes.hes-so.ch/record/15090}, doi = {https://doi.org/10.1039/D4MR00097H}, }