000014814 001__ 14814
000014814 005__ 20241002132804.0
000014814 022__ $$a09209964
000014814 0247_ $$2DOI$$a10.1016/j.schres.2024.09.022
000014814 037__ $$aARTICLE
000014814 039_9 $$a2024-10-02 13:28:04$$b0$$c2024-10-01 16:14:22$$d1000086$$c2024-10-01 16:13:47$$d0$$c2024-10-01 15:52:31$$d1000086$$c2024-10-01 15:51:58$$d1000086$$y2024-09-30 11:29:26$$z1000076
000014814 041__ $$aeng
000014814 245__ $$aWinter birth :$$ba factor of poor functional outcome in a Swiss early psychosis cohort
000014814 260__ $$a-$$bElsevier
000014814 269__ $$a2024-12
000014814 300__ $$a6 p.
000014814 506__ $$avisible
000014814 520__ $$9eng$$aObjective: Winter birth has consistently been identified as a risk factor for schizophrenia. This study aimed to 
determine whether individuals born during this season are also at higher risk for early psychosis and whether this is associated with distinct functional and clinical outcomes.
Methods: We conducted a prospective study on 222 patients during their early phase of psychosis in Switzerland, nested in the Treatment and Early Intervention in Psychosis (TIPP) cohort. We compared the birth trimesters of these patients with those of the general Swiss population. Additionally, we evaluated the Global Assessment of Functioning scale (GAF) and the Positive and Negative Syndrome Scale (PANSS) scores among patients born in winter (January to March) versus those born during the rest of the year during a three-year follow-up period.
Results: A significantly higher proportion of patients experiencing early psychosis were born in winter compared to the general Swiss population. Patients born in winter had significantly lower GAF scores at 6 months, 24 months, and 36 months of follow-up, compared to patients born during the rest of the year. They also manifested fewer positive symptoms, as indicated by the PANSS positive subscale.
Conclusion: Birth in winter appears to be associated with a lower functional outcome and potentially distinct 
symptomatology in the early phase of psychosis
000014814 540__ $$acorrect
000014814 592__ $$aLa Source
000014814 592__ $$bSecteur Recherche et Développement (Ra&D) de l'Institut et Haute Ecole de la Santé La Source
000014814 592__ $$cSanté
000014814 65017 $$aSanté
000014814 6531_ $$9eng$$aschizophrenia
000014814 6531_ $$9eng$$aseason of birth
000014814 6531_ $$9eng$$aTIPP
000014814 6531_ $$9eng$$apsychosis
000014814 6531_ $$9eng$$afunctional outcome
000014814 6531_ $$9eng$$awinter birth
000014814 655__ $$ascientifique
000014814 700__ $$aRestellini, Romeo$$uService of General Psychiatry, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland; Center for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland; Service of Emergency Medicine, Department of Acute Medicine, Geneva University Hospitals, Geneva, Switzerland
000014814 700__ $$aGolay, Philippe$$uService of General Psychiatry, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland; La Source School of Nursing, HES-SO, Lausanne
000014814 700__ $$aJenni, Raoul$$uCenter for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland
000014814 700__ $$aBaumann, Philipp S.$$uService of General Psychiatry, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland
000014814 700__ $$aAlameda, Luis$$uService of General Psychiatry, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland; Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College of London, London, UK; Centro Investigacion Biomedica en Red de Salud Mental (CIBERSAM), Instituto de Biomedicina de Sevilla (IBIS), Hospital Universitario Virgen del Rocio, Departamento de Psiquiatria, Universidad de Sevilla, Sevilla, Spain
000014814 700__ $$aAllgäuer, Larissa$$uCenter for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland
000014814 700__ $$aSteullet, Pascal$$uCenter for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland
000014814 700__ $$aAbrahamyan Empson, Lilith$$uService of General Psychiatry, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland
000014814 700__ $$aMebdouhi, Nadir$$uService of General Psychiatry, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland
000014814 700__ $$aQuang Do, Kim$$uCenter for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland
000014814 700__ $$aConus, Philippe$$uService of General Psychiatry, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland
000014814 700__ $$aDwir, Daniella$$uCenter for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland
000014814 700__ $$aKlauser, Paul$$uCenter for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland; Service of Child and Adolescent Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland
000014814 773__ $$tSchizophrenia Research$$j274$$q206-211
000014814 8564_ $$9d904f219-dfe0-4bef-bbf7-b2ef4fc1ed14$$s849231$$uhttps://arodes.hes-so.ch/record/14814/files/RestelliniEtal_2024_Winter_birth.pdf
000014814 906__ $$aGOLD
000014814 909CO $$ooai:hesso.tind.io:14814$$pGLOBAL_SET
000014814 950__ $$aSan2
000014814 980__ $$ascientifique
000014814 981__ $$ascientifique