Access to images in scientific publications overall and in the biomedical domain specifically, has long been established a desirable feature for services providing access to scientific literature [2,6]. Likewise, automatic identification of regions of interest in clinical images and image-based assisted diagnosis are widely recognized as a means for bringing potentially important health issues to clinicians’ attention [11]. The individual research efforts in addressing these needs were faced with the lack of resources for development and evaluation of image search engines and tools for understanding image content.